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Offline Isaac Adeniran

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Monkeypox-causes, management and prevention
« on: October 06, 2017, 04:35:32 AM »
Monkeypox is a rare disease that is caused by infection with monkeypox virus. Monkeypox virus belongs to the Orthopoxvirus genus in the family Poxviridae. The Orthopoxvirus genus also includes variola virus (the cause of smallpox), vaccinia virus (used in the smallpox vaccine), and cowpox virus.

Monkeypox was first discovered in 1958 when two outbreaks of a pox-like disease occurred in colonies of monkeys kept for research, hence the name ‘monkeypox.’ The first human case of monkeypox was recorded in 1970 in the Democratic Republic of Congo during a period of intensified effort to eliminate smallpox. Since then monkeypox has been reported in humans in other central and western African countries (see table below). The 2003 outbreak in the United States is the only time monkeypox infections in humans were documented outside of Africa.

The natural reservoir of monkeypox remains unknown. However, African rodent species are expected to play a role in transmission.

There are two distinct genetic groups (clades) of monkeypox virus—Central African and West African. West African monkeypox is associated with milder disease, fewer deaths, and limited human-to-human transmission.

Count   Years   Recorded Human Cases
Cameroon   1976
1990   2
4
Central African Republic   1984   6
Democratic Republic of Congo   Endemic   
Gabon   1987
1991   3
5
Ivory Coast   1971
1981   1
1
Liberia   1970   4
Nigeria   1971
1978   2
1
Republic of Congo   Sporadic   
Sierra Leone   1970
2014   1
1
Sudan   2005   19
United States   2003   47
R


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Monkeypox-causes, management and prevention
« on: October 06, 2017, 04:35:32 AM »

Offline Isaac Adeniran

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transmissions of Monkeypox
« Reply #1 on: October 06, 2017, 04:37:41 AM »
Transmission of Monkeypox
 
Transmission of monkeypox virus occurs when a person comes into contact with the virus from an animal, human, or materials contaminated with the virus. The virus enters the body through broken skin (even if not visible), respiratory tract, or the mucous membranes (eyes, nose, or mouth). Animal-to-human transmission may occur by bite or scratch, bush meat preparation, direct contact with body fluids or lesion material, or indirect contact with lesion material, such as through contaminated bedding. Human-to-human transmission is thought to occur primarily through large respiratory droplets. Respiratory droplets generally cannot travel more than a few feet, so prolonged face-to-face contact is required. Other human-to-human methods of transmission include direct contact with body fluids or lesion material, and indirect contact with lesion material, such as through contaminated clothing or linens.

The reservoir host (main disease carrier) of monkeypox is still unknown although African rodents are suspected to play a part in transmission. The virus that causes monkeypox has only been recovered (isolated) twice from an animal in nature. In the first instance (1985), the virus was recovered from an apparently ill African rodent (rope squirrel) in the Equateur Region of the Democratic Republic of Congo. In the second (2012), the virus was recovered from a dead infant mangabey found in the Tai National Park, Cote d’Ivoire.

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transmissions of Monkeypox
« Reply #1 on: October 06, 2017, 04:37:41 AM »

Offline Isaac Adeniran

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Signs and Symptoms on Monkeypox
« Reply #2 on: October 06, 2017, 04:39:35 AM »
Signs and Symptoms on Monkeypox

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In humans, the symptoms of monkeypox are similar to but milder than the symptoms of smallpox. Monkeypox begins with fever, headache, muscle aches, and exhaustion. The main difference between symptoms of smallpox and monkeypox is that monkeypox causes lymph nodes to swell (lymphadenopathy) while smallpox does not. The incubation period (time from infection to symptoms) for monkeypox is usually 7−14 days but can range from 5−21 days.

The illness begins with:

Fever
Headache
Muscle aches
Backache
Swollen lymph nodes
Chills
Exhaustion
Within 1 to 3 days (sometimes longer) after the appearance of fever, the patient develops a rash, often beginning on the face then spreading to other parts of the body.

Lesions progress through the following stages before falling off:

Macules
Papules
Vesicles
Pustules
Scabs
The illness typically lasts for 2−4 weeks. In Africa, monkeypox has been shown to cause death in as many as 1 in 10 persons who contract the disease.

NaijaSky

Signs and Symptoms on Monkeypox
« Reply #2 on: October 06, 2017, 04:39:35 AM »

Offline Isaac Adeniran

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Prevention of Monkeypox
« Reply #3 on: October 06, 2017, 04:42:00 AM »
Prevention of Monkeypox
 
Practice good hand hygiene after contact with infected animals or humans.

There are number of measures that can be taken to prevent infection with monkeypox virus:

Avoid contact with animals that could harbor the virus (including animals that are sick or that have been found dead in areas where monkeypox occurs).
Avoid contact with any materials, such as bedding, that has been in contact with a sick animal.
Isolate infected patients from others who could be at risk for infection.
Practice good hand hygiene after contact with infected animals or humans. For example, washing your hands with soap and water or using an alcohol-based hand sanitizer.
Use personal protective equipment (PPE) when caring for patients.
Personal Protective Equipment Resources

Personal Protection Equipment (PPE)
Sequence for Putting on Personal Protection Equipment (PPE)[PDF – 2.85MB]
Select Your PPE Equipment Combination
Guidance for the Selection and Use of Personal Protective Equipment (PPE) in Healthcare Settings

NaijaSky

Prevention of Monkeypox
« Reply #3 on: October 06, 2017, 04:42:00 AM »


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